ALPINE
A semi-supervised NMF framework that separates phenotype- and batch-associated signals from shared biological variation in multicondition single-cell RNA-seq data.
Single-cell RNA-seqPhenotype decodingInterpretable NMFBatch correction
Research software
Software developed alongside my research for extracting biological signal from complex single-cell and epigenomic data.
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A semi-supervised NMF framework that separates phenotype- and batch-associated signals from shared biological variation in multicondition single-cell RNA-seq data.
A cancer label-free framework for estimating tumor purity and recovering tumor-intrinsic, CpG-resolved profiles from bulk DNA methylation data.